AZ5104

Manufacturer	TargetMol
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Amount	10mM*1mL(inDMSO)
Item no.	TMO-T2491-10mM
CASRN	1421373-98-9
eClass 6.1	32169090
eClass 9.0	32169090
Available
Description	AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R/T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively. Phase 1.
Formulate	C27H31N7O2
Shipping temperature	Cool Pack
Smeles	COC1=C(NC2=NC=CC(=N2)C2=CNC3=CC=CC=C23)C =C(NC(=O)C=C)C(=C1)N(C)CCN(C)C
Storage Temperature	-20C
Target's name	EGFR inhibitor, IGF-1R inhibitor, TGF-beta/Smad inhibitor, ALK

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Amount: 10mM*1mL(inDMSO)

available

Delivery expected until 5/23/2024