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Binimetinib

Binimetinib

Item no.	TMO-T2508-10mM
Manufacturer	TargetMol
CASRN	606143-89-9
Amount	10 mM x 1 mL (in DMSO)
Quantity options	100 mg 10 mM x 1 mL (in DMSO) 10 mg 1 mL 200 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	Cn1cnc2c(F)c(Nc3ccc(Br)cc3F)c(cc12)C(=O)NOCCO
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	MEK162, ARRY-162, ARRY-438162
Shipping condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|MEK
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	441, 23
Description	Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation.
Formulate	C17H15BrF2N4O3
Pathways	Autophagy\|\|\|MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mM x 1 mL (in DMSO)

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