« Back
Home /
Linifanib

Linifanib

Item no.	TMO-T2514-100mg
Manufacturer	TargetMol
CASRN	796967-16-3
Amount	100 mg
Quantity options	100 mg 100 mg 1 mL x 10 mM (in DMSO) 1 mL x 10 mM (in DMSO) 10 mg 10 mg 1 mL 200 mg 200 mg 25 mg 25 mg 2 mg 500 mg 500 mg 50 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ABT-869,RG3635,AL-39324
Shipping Condition	Cool pack
Available
Manufacturer - Targets	VEGFR\|\|\|Apoptosis\|\|\|FLT\|\|\|Autophagy\|\|\|PDGFR\|\|\|c-Fms\|\|\|c-Kit\|\|\|CSF-1R
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	375, 4
Description	Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3).
Pathways	Apoptosis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T2514-100mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question