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Cabozantinib

Cabozantinib

Item no.	TMO-T2586-1ml
Manufacturer	TargetMol
CASRN	849217-68-1
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4(C(NC5=CC=C(F)C=C5)=O)CC4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	XL184,BMS-907351
Similar products	849217-68-1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|c-Met/HGFR\|\|\|VEGFR\|\|\|FLT\|\|\|c-Kit\|\|\|TAM Receptor\|\|\|c-RET
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	501.51
Description	Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity.
Pathways	Apoptosis\|\|\|Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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