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Vismodegib

Vismodegib

Item no.	TMO-T2590-50mg
Manufacturer	TargetMol
CASRN	879085-55-9
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	ClC=1C(=CC(NC(=O)C2=C(Cl)C=C(S(C)(=O)=O)C=C2)=CC1)C3=CC=CC=N3
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	RG 3616,GDC-0449,Erivedge
Similar products	879085-55-9
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ABC Transporter\|\|\|Autophagy\|\|\|Hedgehog/Smoothened
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	421.3
Description	Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).
Pathways	Autophagy\|\|\|Membrane transporter/Ion channel\|\|\|Stem Cells\|\|\|GPCR/G Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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