Comparison

Lumacaftor European Partner

Item no. TMO-T2595-10mM
Manufacturer TargetMol
CASRN 936727-05-8
Amount 1 mL x 10 mM (in DMSO)
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles Cc1ccc(NC(=O)C2(CC2)c2ccc3OC(F)(F)Oc3c2)nc1-c1cccc(c1)C(O)=O
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias VX-809,VRT 826809
Shipping Condition Cool pack
Available
Manufacturer - Targets
Autophagy|||CFTR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
452.41
Description
Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
Pathways
Autophagy|||Membrane transporter/Ion channel
Formulate
C24H18F2N2O5

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL x 10 mM (in DMSO)
Available: In stock
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