Comparison

AG490 European Partner

Item no. TMO-T2600-10mM
Manufacturer TargetMol
CASRN 133550-30-8
Amount 1 mL x 10 mM (in DMSO)
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias AG 490,Tyrphostin B42,Tyrphostin AG 490,AG-490,Zinc02557947
Shipping Condition Cool pack
Available
Manufacturer - Targets
EGFR|||STAT|||JAK|||Autophagy
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
294.3
Description
AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.
Pathways
Stem Cells|||Autophagy|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis
Formulate
C17H14N2O3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL x 10 mM (in DMSO)
Available: In stock
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