Comparison

KN-93 Phosphate European Partner

Item no. TMO-T2606-2mg
Manufacturer TargetMol
CASRN 1913269-12-1
Amount 2 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Citations 1. Sumi M, et al. Biochem Biophys Res Commun. 1991, 181(3), 968-975.
Smiles OP(O)(O)=O.COc1ccc(cc1)S(=O)(=O)N(CCO)c1ccccc1CN(C)C\C=C\c1ccc(Cl)cc1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias CaMK inhibitor
Shipping Condition Cool pack
Available
Manufacturer - Targets
CaMK
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
599.03
Description
KN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase. It is a calcium/calmodulin-dependent kinase II (CaMKII) inhibitor with a Ki of 370 nM. It can also inhibit the proliferation of human hepatic stellate cells.
Pathways
Neuroscience
Bioactivity
KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 uM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities.
Receptor
CaMKII

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2 mg
Available: In stock
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