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Rebastinib

Rebastinib

Item no.	TMO-T2640-10mg
Manufacturer	TargetMol
CASRN	1020172-07-9
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Heart & Blood Cancer
Type	Molecules
Specific against	other
Purity	0,98
Smiles	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc4ncccc4c3)C(C)(C)C)c(F)c2)ccn1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	DCC2036,DCC 2036,DCC-2036
Similar products	1020172-07-9
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Src\|\|\|Apoptosis\|\|\|FLT\|\|\|Bcr-Abl
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	553.59
Description	DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Rebastinib aimed at the Angiopoietin2-Tie2 pathway.
Pathways	Apoptosis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Cytoskeletal Signaling\|\|\|Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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