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Fraxetin

Fraxetin

Item no.	TMO-T2909-25mg
Manufacturer	TargetMol
CASRN	574-84-5
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 50 mg 5 mg
Category	Neuroscience Targets for Rodent Neurosciences Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9889
Citations	1. Wang H, et al. Mol Med Rep. 2014 Nov;10(5):2341-5.
Smiles	COc1cc2ccc(=O)oc2c(O)c1O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	7,8-dihydroxy-6-methoxy coumarin
Similar products	574-84-5
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	208.17
Description	Fraxetin (7, 8-dihydroxy-6-methoxy coumarin) has dual-antioxidative , hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax.
Pathways	Apoptosis

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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