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CZC-25146

CZC-25146

Item no.	TMO-T3053-2mg
Manufacturer	TargetMol
CASRN	1191911-26-8
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Ramsden N, et al. ACS Chem Biol. 2011 Oct 21;6(10):1021-8.
Smiles	COc1cc(ccc1Nc1ncc(F)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CHEMBL2397014
Shipping Condition	Cool pack
Available
Manufacturer - Targets	LRRK2
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	488.54
Description	CZC-25146 (CHEMBL2397014) is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2(Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.
Pathways	Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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