VX-11e

Item no.	TMO-T3166-2mg
Manufacturer	TargetMol
CASRN	896720-20-0
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9892
Citations	1. Aronov AM, et al. J Med Chem. 2009 Oct 22;52(20):6362-8.
Smiles	Cc1cnc(Nc2ccc(F)cc2Cl)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Vertex-11e,VTX-11e,TCS ERK 11e
Shipping Condition	Cool pack
Available
Manufacturer - Targets	CDK\|\|\|Aurora Kinase\|\|\|ERK\|\|\|GSK-3\|\|\|FLT
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	500.35
Description	VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.
Pathways	Tyrosine Kinase/Adaptors\|\|\|Chromatin/Epigenetic\|\|\|PI3K/Akt/mTOR signaling\|\|\|Cell Cycle/Checkpoint\|\|\|Angiogenesis\|\|\|MAPK\|\|\|Stem Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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