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JNJ-42165279

JNJ-42165279

Item no.	TMO-T3215-2mg
Manufacturer	TargetMol
CASRN	1346528-50-4
Amount	2 mg
Quantity options	100 mg 10 mM x 1 mL (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9989
Citations	1.Keith JM, et al. ACS Med Chem Lett. 2015 Nov 2;6(12):1204-8.
Smiles	FC1(F)Oc2ccc(CN3CCN(CC3)C(=O)Nc3cnccc3Cl)cc2O1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	JNJ42165279
Shipping condition	Cool pack
Available
Manufacturer - Targets	FAAH\|\|\|Autophagy
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	410, 8
Target names or alias	JNJ42165279
Description	JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 μM) exhibits high selectivity against a panel of 50 receptors, enzymes, transporters, and ion-channels, at which concentration it does not produce >50% inhibition of binding to any of the targets. Fortunately, JNJ-42165279 (10 μM) also does not inhibit CYPs (1A2, 2C8, 2C9, 2C19, 2D6, 3A4) or hERG.
Pathways	Neuroscience\|\|\|Metabolism\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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