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Xevinapant hydrochloride

Xevinapant hydrochloride

Item no.	TMO-T3299-50mg
Manufacturer	TargetMol
CASRN	1071992-57-8
Amount	50 mg
Quantity options	1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Breast Cancer
Type	Molecules
Specific against	other
Citations	1. Melissa KB, et al. Y Biol Ther. 2012 Jul 1; 13(9): 804–811.
Smiles	Cl.[H][C@]12CC[C@H](N1C(=O)[C@H](CN(CC2)C(=O)CC(C)C)NC(=O)[C@H](C)NC)C(=O)NC(c1ccccc1)c1ccccc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	AT-406 HCl,SM-406
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|IAP
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	598.19
Description	Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
Pathways	Apoptosis

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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