Comparison

AKT inhibitor VIII European Partner

Item no. TMO-T3346-50mg
Manufacturer TargetMol
CASRN 612847-09-3
Amount 50 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Citations 1. Lindsley CW, et al. Bioorg Med Chem Lett. 2005, 15(3), 761-764.
Smiles O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3cc4[nH]cnc4cc3nc2-c2ccccc2)CC1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias AKTi-1/2
Shipping Condition Cool pack
Available
Manufacturer - Targets
Apoptosis|||Akt
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
551.64
Description
AKT inhibitor VIII (AKTi-1/2) is a highly specific inhibitor of Akt1/2, with IC50 values of 58 nM and 210 nM respectively, demonstrating approximately 36-fold greater selectivity for Akt1 over Akt3.
Pathways
Apoptosis|||PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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