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Ginsenoside F1

Ginsenoside F1

Item no.	TMO-T3401-10mM
Manufacturer	TargetMol
CASRN	53963-43-2
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 20 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Citations	1. Kim JH, et al. Exp Dermatol. 2015 Feb;24(2):150-2.
Smiles	CC(C)=CCC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O)C(C)(C)[C@@H]3[C@@H](O)C[C@@]21C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	20(S)-Ginsenoside F1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Endogenous Metabolite\|\|\|Cytochromes P450
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	638.87
Description	Ginsenoside F1 (20(S)-Ginsenoside F1) is an enzymatically modified derivative of ginsenoside Rg1, showing competitive inhibition of the activity of CYP3A4 and a weaker inhibition of the activity of CYP2D6.
Pathways	Metabolism
Bioactivity	Ginsenoside F1, an enzymatically modified derivative of ginsenoside Rg1, protection from ultraviolet-B-induced apoptosis is tightly correlated with ginsenoside-F1-mediated inhibition of ultraviolet-B-induced downregulation of Bcl-2 and Brn-3a expression. Ginsenoside F1 exhibited competitive inhibition of the activity of CYP3A4 with Ki values of 57.7 +/- 9.6 uM and 67.8 +/- 16.2 uM, respectively. Ginsenoside F1 exhibited a weaker inhibition of the activity of CYP2D6.
Receptor	CYP3A4

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Amount: 1 mL x 10 mM (in DMSO)

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