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Fisogatinib

Fisogatinib

Item no.	TMO-T3456-50mg
Manufacturer	TargetMol
CASRN	1707289-21-1
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules Reagents & Chemicals Molecules By Organ Colorectal Cancer Calcium Binding Protein Markers Interneuron Markers
Type	Molecules
Specific against	other
Citations	1.Neil Bifulco, et al. Inhibitors of the fibroblast growth factor receptor. PCT Int. Appl. (2015), WO 2015061572 A1 20150430.
Smiles	COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2nc(N[C@@H]3COCC[C@@H]3NC(=O)C=C)ncc2c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	BLU554,BLU 554,BLU-554
Shipping Condition	Cool pack
Available
Manufacturer - Targets	FGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	503.38
Description	Fisogatinib (BLU-554) is a highly potent, selective and orally active FGFR4 inhibitor with an IC50 value of 5 nM and significant anti-tumor activity in hepatocellular carcinoma models dependent on FGFR4 signaling.
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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