Comparison

Vesnarinone European Partner

Item no. TMO-T3465-25mg
Manufacturer TargetMol
CASRN 81840-15-5
Amount 25 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Citations 1.Katayama Y, et al. Inhibitory effects of Vesnarinone on cloned cardiac delayed rectifier K(+) channels expressed in a mammalian cell line. J Pharmacol Exp Ther. 2000 Jul;294(1):339-46.
Smiles COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias OPC-8212,Arkin,Piteranometozine
Shipping Condition Cool pack
Available
Manufacturer - Targets
HIV Protease|||PDE
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
395.45
Description
Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.
Pathways
Proteases/Proteasome|||Microbiology/Virology|||Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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