CFMTI

Item no.	TMO-T3482-50mg
Manufacturer	TargetMol
CASRN	864864-17-5
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Neuroscience Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1.Satow A et al. Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one. J Pharmacol Exp Ther. 2009 Jul;330(1):179-90.
Smiles	Cc1c(nnn1-c1cccnc1F)-c1ccc2C(=O)N(Cc2c1)C1CC1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	GluR antagonist
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GluR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	349.36
Description	CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000-fold than mGluR5.
Pathways	Neuroscience

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