Comparison

3-MATIDA European Partner

Item no. TMO-T3486-50mg
Manufacturer TargetMol
CASRN 518357-51-2
Amount 50 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Citations 1.Moroni, F., et al.The novel and systemically active metabotropic glutamate 1 (mGlu1) receptor antagonist 3-MATIDA reduces post-ischemic neuronal death.Neuropharmacology. 2002. Neuropharmacology. 42: 741-751.
Smiles C(C(O)=O)(N)C=1SC(C(O)=O)=CC1C
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias GluR antagonist
Shipping Condition Cool pack
Available
Manufacturer - Targets
NMDAR|||GluR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
215.23
Description
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
Pathways
Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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