C29

Item no.	TMO-T3502-5mg
Manufacturer	TargetMol
CASRN	363600-92-4
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Neuroscience Neural Lineage Markers Reagents & Chemicals Molecules Neurodegeneration Markers
Type	Molecules
Specific against	other
Citations	1. Pragnesh Mistry,Inhibition of TLR2 signaling by small molecule inhibitors targeting a novel putative pocket within the TLR2 TIR domain (INM9P.448). J Immunol May 1, 2014, 192 (1 Supplement) 189.1;
Smiles	COc1cccc(\C=N\c2cccc(C(O)=O)c2C)c1O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	TLR inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	TLR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	285.29
Description	C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.
Pathways	Immunology/Inflammation

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