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SEA0400

SEA0400

Manufacturer	TargetMol
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	10mM*1mL(inDMSO)
Item no.	TMO-T3508-10mM
CASRN	223104-29-8
eClass 6.1	32169090
eClass 9.0	32169090
Available
Bioactivity	SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger (IC50s = 5, 8.3, and 33 nM for inhibiting Na+-dependent Ca2+ uptake in rat astrocyte, microglia, and cortical neuron cell lines, respectively). It is reported to prevent dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease and to attenuate reperfusion injury in both in vitro and in vivo cerebral ischemic models.
MolWt	371, 384
Pathways	Membrane transporter/Ion channel
Receptor	NCX

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 10mM*1mL(inDMSO)

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Delivery expected until 5/16/2024