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TRC051384

TRC051384

Item no.	TMO-T3527-25mg
Manufacturer	TargetMol
CASRN	867164-40-7
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Neuroscience Neuroinflammation Protein Aggregation, Clearance & Misfolding Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Mohanan et al. Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer. 2011, Neuropharmacology. 60 991.
Smiles	O=C(NCCN1CCOCC1)Nc1ccc(cc1)C(=O)\C=C\c1cccc(n1)N1CCOCC1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	TRC 051384
Shipping Condition	Cool pack
Available
Manufacturer - Targets	HSP
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	465.54
Description	TRC051384 is a heat shock protein 70 (HSP70) inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke, activates heat shock factor-1 and leads to elevated molecular chaperone and anti-inflammatory activity, and enhances Hsp72 expression in neurons and glial cells.
Pathways	Metabolism\|\|\|Cytoskeletal Signaling

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