IMR-1A

Item no.	TMO-T3540-5mg
Manufacturer	TargetMol
CASRN	331862-41-0
Amount	5 mg
Quantity options	100 mg 10 mM x 1 mL (in DMSO) 10 mg 1 mL 1 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Astudillo L,et al. The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Cancer Res. 2016 Jun 15;76(12):3593-603.
Smiles	COc1cc(\C=C2\SC(=S)NC2=O)ccc1OCC(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Gamma-secretase inhibitor
Shipping condition	Cool pack
Available
Manufacturer - Targets	Drug Metabolite\|\|\|Gamma-secretase
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	325, 36
Description	IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
Pathways	Stem Cells\|\|\|Neuroscience\|\|\|Metabolism\|\|\|Proteases/Proteasome

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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