FIPI

Item no.	TMO-T3580-10mg
Manufacturer	TargetMol
CASRN	939055-18-2
Amount	10 mg
Quantity options	100 mg 10 mM x 1 mL (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Monovich L, et al. Optimization of halopemide for phospholipase D2 inhibition. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2310-1.
Smiles	Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	5-Fluoro-2-indolyl deschlorohalopemide
Shipping condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|Phospholipase
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	421, 47
Target names or alias	5-Fluoro-2-indolyl deschlorohalopemide
Description	FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis.
Pathways	Autophagy\|\|\|Metabolism

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