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Ivosidenib

Ivosidenib

Manufacturer	TargetMol
Category	Oncology Reagents & Chemicals Molecules By Organ Brain Cancer
Type	Molecules
Specific against	other
Amount	50mg
Item no.	TMO-T3617-50mg
CASRN	1448347-49-6
eClass 6.1	32169090
eClass 9.0	32169090
Available
Short Description	Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a mutated form of IDH1 in the cytoplasm, which inhibits the formation of the oncometabolite, 2-hydroxyglutarate (2 hG). This may lead to both an induction of cellular differentiation and an inhibition of cellular proliferation in IDH1-expressing tumor cells.
Shipping	cool pack
Storage	-20°
Target names or alias	AG-120
Molecular Weight	582, 97
Pathway	Metabolism
Target	Dehydrogenase\|\|\|Isocitrate Dehydrogenase (IDH)

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Amount: 50mg

available

Delivery expected until 6/6/2024