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IQ-1S free acid

IQ-1S free acid

Item no.	TMO-T3627-10mM
Manufacturer	TargetMol
CASRN	23146-22-7
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Citations	1. Igor A. Schepetkin et al. J Pharmacol Exp Ther, 2015 Jun, 353(3): 505-516.
Smiles	ON=C1c2ccccc2-c2nc3ccccc3nc12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	IQ-1,IQ-1S (free acid),IQ-1S
Shipping Condition	Cool pack
Available
Manufacturer - Targets	NF-κB\|\|\|JNK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	247.25
Description	IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
Pathways	MAPK\|\|\|NF-κB
Bioactivity	IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis.
Receptor	JNK1; JNK2; JNK3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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