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K-Ras(G12C) Inhibitor 6

K-Ras(G12C) Inhibitor 6

Item no.	TMO-T3725-100mg
Manufacturer	TargetMol
CASRN	2060530-16-5
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton Reagents & Chemicals Molecules By Organ Lung Cancer Colorectal Cancer small GTPases Ras Subfamily
Type	Molecules
Specific against	other
Citations	1. Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8895-900.
Smiles	SCCCC(=O)NC1CCN(CC1)C(=O)COc1ccc(Cl)cc1Cl
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Raf
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	405.33
Description	K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant, achieving 100% protein modification at 10 μM after 24 hours in vitro.
Pathways	MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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