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Velutin

Velutin

Item no.	TMO-T3816-5mg
Manufacturer	TargetMol
CASRN	25739-41-7
Amount	5 mg
Quantity options	1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Metabolism Diabetes Glucose Homeostasis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Xie C, et al. The açai flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-alpha and IL-6 production through inhibiting NF-kappaB activation and MAPK pathway. J Nutr Biochem. 2012 Sep;23(9):1184-91.
Smiles	COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(OC)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NF-kappaB inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	HIF/HIF Prolyl-Hydroxylase\|\|\|NF-κB
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	314.29
Description	Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK phosphorylation. Velutin has anti-inflammatory property. Velutin exhibits the greatest potency among all flavones which reduce TNF-α and IL-6 production.
Pathways	Chromatin/Epigenetic\|\|\|NF-κB\|\|\|Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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