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Acacetin

Acacetin

Item no.	TMO-T3981-25mg
Manufacturer	TargetMol
CASRN	480-44-4
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 500 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Breast Cancer
Type	Molecules
Specific against	other
Citations	1. Zieli?ska, S. and Matkowski, A. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochem. Rev. 13(2), 391-416 (2014).
Smiles	COc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Linarigenin,4'-Methoxyapigenin,5,7-Dihydroxy-4'-methoxyflavone
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|COX\|\|\|Apoptosis\|\|\|IAP
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	284.26
Description	Acacetin (5, 7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, exhibiting antinociceptive, anti-inflammatory, and antioxidant activities in different research models.
Pathways	Neuroscience\|\|\|Immunology/Inflammation\|\|\|Apoptosis\|\|\|Autophagy
Bioactivity	Acacetin has anti-plasmodial activity and anti-peroxidant activity. Also acacetin is an ATP-competitive PI3-K inhibitor. And has anti-cancer and antitumor activities, such as prostate cancer, melanoma angiogenesis tumor , via Akt/NF-kappaB, Stat signaling pathway.Has anti-inflammatory and antiarthritic effects in FLSs, can inhibit p38 and JNK phosphorylation and reduces MMP-1, MMP-3 and MMP-13 expression in interleukin-1beta-induced FLSs.
Receptor	COX-2; XIAP

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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