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Itacitinib

Itacitinib

Item no.	TMO-T3998-5mg
Manufacturer	TargetMol
CASRN	1334298-90-6
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Metabolism Diabetes Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Bissonnette R, et al. A randomized, double-blind, placebo-controlled, dose-escalation study of the safety and efficacy of INCB039110, an oral janus kinase 1 inhibitor, in patients with stable, chronic plaque psoriasis. J Dermatolog Treat. 2016 Aug;27(4):332-8.
Smiles	Fc1c(ccnc1C(F)(F)F)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	INCB39110,INCB039110
Shipping Condition	Cool pack
Available
Manufacturer - Targets	JAK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	553.51
Description	Itacitinib (INCB039110) is an orally bioavailable Janus-associated kinase 1 (JAK1) inhibitor with potential antineoplastic activity.
Pathways	Tyrosine Kinase/Adaptors\|\|\|Angiogenesis\|\|\|JAK/STAT signaling\|\|\|Stem Cells\|\|\|Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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