Comparison

CP-724714 European Partner

Item no. TMO-T4014-25mg
Manufacturer TargetMol
CASRN 383432-38-0
Amount 25 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Citations 1.Jani JP, et al. Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor. Cancer Res, 2007, 67(20), 9887-9893.
Smiles COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias CP724714,CP 724714
Shipping Condition Cool pack
Available
Manufacturer - Targets
Apoptosis|||EGFR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
469.54
Description
CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2, c-Met etc.
Pathways
Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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