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HG-14-10-04

HG-14-10-04

Item no.	TMO-T4015-10mM
Manufacturer	TargetMol
CASRN	1356962-34-9
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Citations	1.U.S. Pat. Appl. Publ. (2012), US 20120028924 A1
Smiles	COc1cc(ccc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12)N1CCC(CC1)N1CCN(C)CC1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ALK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	532.08
Description	HG-14-10-04 is a potent and specific ALK (anaplastic lymphoma kinase) inhibitor.
Pathways	Tyrosine Kinase/Adaptors\|\|\|Angiogenesis
Bioactivity	HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM. IC50 value: 20 nM Target: ALK More information can be found in the following Patent, Example 10 Preparation of substituted pyrimidinamines as ALK kinase inhibitors By Aquila, Brian; Kamhi, Victor; Peng, Bo; Pontz, Timothy; Saeh, Jamal Carlos; Thakur, Kumar; Yang, Bin From U.S. Pat. Appl. Publ. (2012), US 20120028924 A1 20120202.
Receptor	ALK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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