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UNC3866

UNC3866

Item no.	TMO-T4021-10mM
Manufacturer	TargetMol
CASRN	1872382-47-2
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1.Stuckey JI, et al. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat Chem Biol. 2016 Mar;12(3):180-7.
Smiles	CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Histone Methyltransferase antagonist
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Histone Methyltransferase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	795.02
Description	UNC3866 is a potent antagonist of the CBX7-H3 interaction, as determined by AlphaScreen.
Pathways	Chromatin/Epigenetic
Bioactivity	UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66+/-1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
Receptor	CBX7-H3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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