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Dantrolene sodium hemiheptahydrate

Dantrolene sodium hemiheptahydrate

Item no.	TMO-T4054-100mg
Manufacturer	TargetMol
CASRN	24868-20-0
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 1 g 1 mL 200 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Leslie GC., et al. The action of dantrolene sodium on rat fast and slow muscle in vivo. Br J Pharmacol. 1981 Apr;72(4):665-72.
Smiles	O.O.O.O.O.O.O.[NaH].[NaH].[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)NC2=O)o1.[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)NC2=O)o1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,Sodium dantrolene
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|Calcium Channel
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	399.29
Description	Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction. Dantrolene sodium hemiheptahydrate (Sodium dantrolene) is the sodium salt form of dantrolene, a hydantoin derivative, and direct-acting skeletal muscle relaxant.
Pathways	Membrane transporter/Ion channel\|\|\|Autophagy\|\|\|Metabolism

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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