R-IMPP

Item no.	TMO-T4058-1mg
Manufacturer	TargetMol
CASRN	2133832-83-2
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Lipoprotein Receptors & Associated Proteins Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Petersen DN., et al. A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. Cell Chem Biol. 2016 Nov 17;23(11):1362-1371.
Smiles	COc1ccc(CCC(=O)N([C@@H]2CCCNC2)c2nccc3ccccc23)cc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Serine/threonin kinase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	389.49
Description	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
Pathways	Cell Cycle/Checkpoint\|\|\|Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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