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Thymoquinone

Thymoquinone

Item no.	TMO-T4088-50mg
Manufacturer	TargetMol
CASRN	490-91-5
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 1 g 200 mg 500 mg 50 mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Reagents & Chemicals Molecules By Organ Heart & Blood Cancer
Type	Molecules
Specific against	other
Citations	1. Randhawa, M.A., and Alghamdi, M.S. Anticancer activity of Nigella sativa (black seed) - A review. Am.J.Chin.Med. 39(6), 1075-1091 (2011).
Smiles	CC(C)C1=CC(=O)C(C)=CC1=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NSC 2228,Thymoquinon
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Bcl-2 Family
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	164.2
Description	Thymoquinone (NSC 2228) is a compound be found in herbs and spices with anti-inflammatory and anti-oxidant effects.
Pathways	Apoptosis
Bioactivity	It has anti-inflammatory effects, blocking the synthesis of leukotrienes.2, 1 Thymoquinone inhibits the growth of leukemia cells (IC50 = 1.5 ug/ml), inducing apoptosis by down-regulating the expression of Bcl-2 while up-regulating Bax expression.3 In addition to blocking cell proliferation and triggering apoptosis, thymoquinone (15 uM) suppresses STAT3-regulated gene expression and prevents angiogenesis.4, 5
Receptor	Bcl-2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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