AS8351

Item no.	TMO-T4100-10mM
Manufacturer	TargetMol
CASRN	796-42-9
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Lung Cancer
Type	Molecules
Specific against	other
Citations	1. Cao, N.,Huang, et al. Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science 352(6290), 1216-1220 (2016).
Smiles	NN(\C=C1/C(=O)C=Cc2ccccc12)C(=O)c1ccncc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NSC51355,AS-8351,AS 8351
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Histone Demethylase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	291.3
Description	AS8351 (NSC51355) is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
Pathways	Chromatin/Epigenetic
Bioactivity	AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
Receptor	Demethylase

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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