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PKM2-IN-1

PKM2-IN-1

Item no.	TMO-T4170-200mg
Manufacturer	TargetMol
CASRN	94164-88-2
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Metabolism Glucose Homeostasis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Ning X, et al. Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase. Eur J Med Chem. 2017 Sep 29;138:343-352.
Smiles	CC1=C(CSC(=S)N2CCCCC2)C(=O)c2ccccc2C1=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PKM2 inhibitor,compound 3k
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PKM
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	345.48
Description	PKM2-IN-1 (compound 3k) exhibits inhibitory activity against PKM2 with an IC50 of 2.95 μM, while the IC50 for PKM1 is 4-5 times higher.
Pathways	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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