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TAK-659 hydrochloride

TAK-659 hydrochloride

Item no.	TMO-T4209-25mg
Manufacturer	TargetMol
CASRN	1952251-28-3
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Citations	1. Lam B, et al. Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK). Bioorg Med Chem Lett. 2016 Dec 15;26(24):5947-5950.
Smiles	Cl.Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	TAK-659
Shipping Condition	Cool pack
Available
Manufacturer - Targets	VEGFR\|\|\|FLT\|\|\|JAK\|\|\|Syk\|\|\|Tyrosine Kinases
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	380.85
Description	TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
Pathways	Stem Cells\|\|\|Tyrosine Kinase/Adaptors\|\|\|Chromatin/Epigenetic\|\|\|Angiogenesis\|\|\|JAK/STAT signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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