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PF-06260933

PF-06260933

Item no.	TMO-T4221-2mg
Manufacturer	TargetMol
CASRN	1811510-56-1
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9997
Citations	1. Ammirati M, et al. Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment. ACS Med Chem Lett. 2015 Oct 6;6(11):1128-33.
Smiles	Nc1ccc(cn1)-c1cnc(N)c(c1)-c1ccc(Cl)cc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PF-6260933,PF 6260933,PF6260933
Shipping Condition	Cool pack
Available
Manufacturer - Targets	MAPK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	296.75
Description	PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.
Pathways	MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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