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Roblitinib

Roblitinib

Item no.	TMO-T4235-25mg
Manufacturer	TargetMol
CASRN	1708971-55-4
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules Reagents & Chemicals Molecules By Organ Colorectal Cancer Calcium Binding Protein Markers Interneuron Markers
Type	Molecules
Specific against	other
Citations	1. WO2015059668A1
Smiles	COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	FGF-401
Shipping Condition	Cool pack
Available
Manufacturer - Targets	FGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	506.56
Description	Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits FGFR4, leading to the inhibition of tumor cell proliferation in FGFR4-overexpressing cells. It is a receptor tyrosine kinase upregulated in certain tumor cells and involved in proliferation, differentiation, angiogenesis, and survival.
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

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Amount: 25 mg

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