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Palifosfamide

Palifosfamide

Item no.	TMO-T4350-50mg
Manufacturer	TargetMol
CASRN	31645-39-3
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Bone Cancer
Type	Molecules
Specific against	other
Citations	1.Hingorani P, et al. Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma. Cancer Chemother Pharmacol. 2009 Sep;64(4):733-40.
Smiles	P(NCCCl)(NCCCl)(=O)O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	ZIO-201,Isophosphamide mustard,Isophosphoramide mustard
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Drug Metabolite\|\|\|DNA Alkylator/Crosslinker\|\|\|DNA Alkylation
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	221.02
Description	Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to 6.75 μM for most cell lines except OS222 (IC50=31.5 μM).
Pathways	DNA Damage/DNA Repair\|\|\|Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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