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GIBH-130

GIBH-130

Item no.	TMO-T4450-50mg
Manufacturer	TargetMol
CASRN	1252608-59-5
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9986
Citations	1.Zhou W, Zhong G, Fu S, et al. Microglia-Based Phenotypic Screening Identifies a Novel Inhibitor of Neuroinflammation Effective in Alzheimer's Disease Models[J]. Acs Chemical Neuroscience, 2016, 7(11):1499-1507.
Smiles	Cc1cc(nnc1C(=O)N1CCN(CC1)c1ncccn1)-c1ccccc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	IL Receptor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	IL Receptor\|\|\|Interleukin\|\|\|TNF
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	360.41
Description	GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
Pathways	Apoptosis\|\|\|Immunology/Inflammation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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