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Simeprevir

Simeprevir

Item no.	TMO-T4686-10mg
Manufacturer	TargetMol
CASRN	923604-59-5
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9961
Citations	1.Lin TI, et al. In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor.Antimicrob Agents Chemother. 2009 Apr;53(4):1377-85. Epub 2009 Jan 26.
Smiles	COc1ccc2c(O[C@@H]3C[C@@H]4[C@@H](C3)C(=O)N(C)CCCC\C=C/[C@@H]3C[C@]3(NC4=O)C(=O)NS(=O)(=O)C3CC3)cc(nc2c1C)-c1nc(cs1)C(C)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	TMC435,TMC-435350,Olysio
Shipping Condition	Cool pack
Available
Manufacturer - Targets	SARS-CoV\|\|\|HCV Protease
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	749.94
Description	Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
Pathways	Microbiology/Virology\|\|\|Proteases/Proteasome

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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