Comparison

Brivanib European Partner

Item no. TMO-T6036-10mM
Manufacturer TargetMol
CASRN 649735-46-6
Amount 1 mL x 10 mM (in DMSO)
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Purity 0,98
Smiles C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias BMS-540215
Shipping Condition Cool pack
Available
Manufacturer - Targets
Autophagy|||FGFR|||VEGFR|||EGFR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
370.38
Description
Brivanib (BMS-540215) is an ATP-competitive inhibitor targeting VEGFR2 with an IC50 of 25 nM, exhibiting moderate potency against VEGFR-1 and FGFR-1, and over 240-fold selectivity against PDGFR-β. Phase 3.
Pathways
Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||JAK/STAT signaling
Formulate
C19H19FN4O3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL x 10 mM (in DMSO)
Available: In stock
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