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URMC-099

URMC-099

Item no.	TMO-T6057-1ml
Manufacturer	TargetMol
CASRN	1229582-33-5
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)CC1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Similar products	1229582-33-5
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Syk\|\|\|Src\|\|\|Aurora Kinase\|\|\|LRRK2\|\|\|SGK\|\|\|c-Met/HGFR\|\|\|DNA Alkylation\|\|\|ROCK\|\|\|MLK\|\|\|VEGFR\|\|\|MEK\|\|\|Bcr-Abl\|\|\|CDK\|\|\|Trk receptor\|\|\|IGF-1R\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	421.54
Description	URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
Pathways	Cell Cycle/Checkpoint\|\|\|Tyrosine Kinase/Adaptors\|\|\|Cytoskeletal Signaling\|\|\|DNA Damage/DNA Repair\|\|\|Metabolism\|\|\|Stem Cells\|\|\|Autophagy\|\|\|Angiogenesis\|\|\|Chromatin/Epigenetic\|\|\|MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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