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Mirdametinib

Mirdametinib

Item no.	TMO-T6189-200mg
Manufacturer	TargetMol
CASRN	391210-10-9
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,995
Citations	1. Barrett SD, et al. Bioorg Med Chem Lett, 2008, 18(24), 6501-6504.
Smiles	OC[C@@H](O)CONC(=O)C1=CC=C(F)C(F)=C1NC1=CC=C(I)C=C1F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PD325901,PD0325901
Shipping Condition	Cool pack
Available
Manufacturer - Targets	MEK\|\|\|Apoptosis\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	482.19
Description	Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis.
Pathways	Autophagy\|\|\|MAPK\|\|\|Apoptosis

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