AT7519

Item no.	TMO-T6205-100mg
Manufacturer	TargetMol
CASRN	844442-38-2
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Metabolism Diabetes Neural Signaling Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Citations	1. Squires MS, et al. Mol Cancer Ther, 2009, 8(2), 324-332.
Smiles	N(C(=O)C1=C(Cl)C=CC=C1Cl)C=2C(C(NC3CCNCC3)=O)=NNC2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CDK inhibitor,GSK-3 inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GSK-3\|\|\|Apoptosis\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	382.24
Description	AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.
Pathways	PI3K/Akt/mTOR signaling\|\|\|Stem Cells\|\|\|Cell Cycle/Checkpoint\|\|\|Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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