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Talazoparib

Talazoparib

Item no.	TMO-T6253-1mg
Manufacturer	TargetMol
CASRN	1207456-01-6
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9985
Citations	1. Wang B, et al. Molecular Cancer Therapeutics, 2009, 8 (12 Suppl), A121.
Smiles	Cn1ncnc1[C@@H]1[C@H](Nc2cc(F)cc3c2c1n[nH]c3=O)c1ccc(F)cc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	LT-673,BMN-673
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PARP
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	380.35
Description	Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
Pathways	Chromatin/Epigenetic\|\|\|DNA Damage/DNA Repair
Bioactivity	Talazoparib(IC50=0.58 nM), a new-type PARP inhibitor, effectively inhibits PARP-2, and is very sensitive to PTEN mutation. Talazoparibbut does not inhibit PARG.
Receptor	PARP

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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